主要的医疗组织和科学团体正在对特朗普政府周一的断言做出反应，该断言称，在怀孕期间使用对乙酰氨基酚是药物泰诺的主要成分，可能与自闭症有关，尽管有限的证据表明这种联系。
在白宫的一次新闻发布会上，唐纳德·特朗普总统表示，食品药品监督管理局(FDA)将立即开始通知医生，“强烈建议女性在怀孕期间限制泰诺的使用，除非有医学上的必要”，FDA将更新对乙酰氨基酚的标签，增加有关可能联系的信息。
此外，川普和卫生与公众服务部部长小罗伯特·F·肯尼迪暗示，儿童疫苗接种计划可能会导致自闭症，这与多年来发现两者之间没有联系的研究相矛盾。
一些团体表示，对乙酰氨基酚是孕妇服用的安全药物，没有研究发现怀孕期间使用和自闭症之间有直接的因果关系。
其他人说，也没有发现疫苗会导致自闭症，疫苗接种计划是安全的。
关于泰诺
美国妇产科医师学会(ACOG)强烈拒绝该声明将怀孕期间服用对乙酰氨基酚与自闭症联系起来，称其“高度关注”，“不负责任”，“没有充分的科学证据支持”
该小组强调，20多年的研究表明，怀孕期间使用对乙酰氨基酚与自闭症、注意力缺陷/多动症或智力残疾之间没有联系，并特别指出了两项高质量的研究。
ACOG公司总裁史蒂文·j·弗莱舍曼博士在一份声明中说:“对乙酰氨基酚是孕妇可以用来治疗疼痛和发烧的少数几种选择之一，如果不及时治疗，可能会对孕妇造成伤害。”“母体发热、作为先兆子痫早期迹象的头痛和疼痛都可以通过对乙酰氨基酚的治疗应用来控制，使对乙酰氨基酚成为需要它的人的必需。”
声明接着说，“人们在怀孕期间使用对乙酰氨基酚进行治疗的情况远比任何理论上的风险更危险，会给孕妇和胎儿带来严重的发病率和死亡率。”
同样，母胎医学学会(SMFM)重申建议对乙酰氨基酚是治疗怀孕期间疼痛和发烧的“适当药物”。
该组织还表示，如果发烧和疼痛得不到治疗，孕妇将面临风险。
SMFM在一份声明中说:“重要的是要明白，怀孕期间未经治疗的发烧和疼痛会给母婴健康带来重大风险。”。“未经治疗的发热，尤其是在妊娠早期，会增加流产、出生缺陷和早产的风险，未经治疗的疼痛会导致产妇抑郁、焦虑和高血压。”
关于疫苗
在新闻发布会上，医疗团体也对疫苗可能导致自闭症的说法做出了回应，尽管几十年来的许多研究都没有发现这种联系。
特朗普在新闻发布会上表示，阿米什儿童没有接种疫苗，因此没有接受自闭症诊断，尽管在阿米什儿童中发现自闭症的研究和并非所有的阿米什儿童都没有接种疫苗.
美国儿科学会(AAP)，代表儿科医生的国家领导团体，参照权利要求被认为是“危险的”,肯定会让家长们感到困惑。
该组织在一份声明中说:“研究一再发现，挽救生命的儿童疫苗和自闭症之间没有可信的联系。”“这项研究在许多国家进行，涉及数千人，历时数十年。任何歪曲科学的努力都会对儿童的健康造成威胁。”
特朗普周一还声称，儿童在生命早期接种了太多疫苗，似乎暗示儿童的免疫系统被疫苗接种淹没了。
研究，如2018年的研究涉及约1000名美国儿童发现疫苗不会压倒或削弱免疫系统，也不会使儿童更容易受到其他感染。
“儿科医生直接了解到，儿童的免疫系统在接种了预防小儿麻痹症、麻疹、百日咳和乙型肝炎等严重传染性疾病的疫苗后表现更好，”AAP表示。“间隔或推迟疫苗接种意味着儿童在最危险的时候对这些疾病没有免疫力。”
关于醛氢叶酸
特朗普政府周一还宣布，它正在启动一种名为醛氢叶酸的药物的批准程序，这种药物可能用于治疗自闭症。
醛氢叶酸通常被用作癌症治疗的一部分，在一些小型研究中显示出早期前景，表明它可能有助于改善一些自闭症儿童的症状，但专家警告说，几乎没有证据支持这些说法。
自闭症科学家联盟发表声明警告说现在推荐亚叶酸钙作为治疗还为时过早。
该组织表示，有一些检查药物使用的小型试验在方法上是薄弱的，使用了有问题的统计方法，并且没有证明临床建议的合理性。
“自闭症科学家联盟审查了这些研究，发现研究人员没有使用高质量的研究设计或统计分析，”该组织表示。
该联盟呼吁进行一项严格的、大规模的试验，使用经过验证的生物标志物和预先注册的终点。该组织还重申，疫苗是安全的，对自闭症没有作用，破坏疫苗会危及公共健康。该组织呼吁卫生与公众服务部投资于高质量的、同行评审的、有独立监督的自闭症研究。
此外，美国自闭症协会(ASA)谴责白宫宣传它所说的关于病因和治疗的“毫无根据”的说法。
该小组强调，自闭症是一种终身的复杂疾病，没有单一的原因或治愈方法，关于对乙酰氨基酚或亚叶酸钙的过早说法忽视了几十年的严格研究，并有可能造成虚假的希望和伤害。
ASA表示，对高剂量亚叶酸钙的研究仍处于初步阶段，在推荐用于自闭症患者之前，必须了解其安全性。
美国自闭症协会董事会在一份声明中说:“在没有严格的、可重复的科学的情况下宣布病因或治疗方法，会破坏信任，分散对自闭症社区所需的关键工作的注意力。”声明。“自闭症患者及其护理人员需要的是扩展的服务、包容性的政策和有助于提高生活质量的研究。”
'Highly concerning': Major medical groups react to Trump's claim that Tylenol is linked to autism
Major medical organizations and scientific groups are reacting to the Trump administration's assertion on Monday that the use of acetaminophen during pregnancy, the main ingredient in the drug Tylenol,may be linked to autism, despite limited evidence to suggest the association.
During a press conference at the White House, President Donald Trump said the Food and Drug Administration (FDA) will begin notifying physicians immediately that it is "strongly recommending that women limit Tylenol use during pregnancy unless medically necessary" and that the FDA would update the label for acetaminophen with enhanced information about the possible link.
Additionally, Trump and Health and Human Services Secretary Robert F. Kennedy Jr. suggested the childhood vaccine schedule could contribute to autism, contradicting years of research that has found no link between the two.
Some groups stated that acetaminophen is a safe medication for pregnant women to take and that no studies have found a direct cause-and-effect between use in pregnancy and autism.
Others said vaccines have also not been found to cause autism and that the vaccine schedule is safe.
On Tylenol
The American College of Obstetricians and Gynecologists (ACOG)strongly rejectedthe claim linking acetaminophen in pregnancy to autism, calling it "highly concerning," "irresponsible" and "not backed by the full body of scientific evidence."
The group emphasized that more than 20 years of research show no link between acetaminophen use during pregnancy and autism, attention-deficit/hyperactivity disorder or intellectual disability, specifically pointing to two high-quality studies.
"Acetaminophen is one of the few options available to pregnant patients to treat pain and fever, which can be harmful to pregnant people when left untreated," Dr. Steven J. Fleischman, president of ACOG, said in a statement. "Maternal fever, headaches as an early sign of preeclampsia, and pain are all managed with the therapeutic use of acetaminophen, making acetaminophen essential to the people who need it."
The statement went on, "The conditions people use acetaminophen to treat during pregnancy are far more dangerous than any theoretical risks and can create severe morbidity and mortality for the pregnant person and the fetus."
Similarly, the Society for Maternal-Fetal Medicine (SMFM)reiterateda recommendation that acetaminophen is an "appropriate medication" to treat pain and fever during pregnancy.
The group also stated that pregnant people face risks when fever and pain are left untreated.
"It is important to understand that untreated fever and pain during pregnancy carry significant maternal and infant health risks," SMFM said in a statement. "Untreated fever, particularly in the first trimester, increases the risk of miscarriage, birth defects, and premature birth, and untreated pain can lead to maternal depression, anxiety, and high blood pressure."
On vaccines
Medical groups also reacted to claims during the press conference that vaccines may cause autism, despite many studies over decades finding no such link.
Trump suggested during the press conference that Amish children do not get vaccines and therefore do not receive autism diagnoses, despitestudies that have identified autism in Amish childrenandthat not all Amish children are unvaccinated.
The American Academy of Pediatrics (AAP), the nation's leading group representing pediatricians,referred to the claimsas "dangerous" and bound to be confusing for parents.
"Studies have repeatedly found no credible link between life-saving childhood vaccines and autism," the group said in a statement. "This research, in many countries, involving thousands of individuals, has spanned multiple decades. Any effort to misrepresent sound, strong science poses a threat to the health of children."
Trump also claimed on Monday that children get too many shots early in life, seeming to imply that children's immune systems get overwhelmed by vaccinations.
Studies, such as a2018 study involving about 1,000 American children, have found that vaccines do not overwhelm or weaken the immune system and don't make children more susceptible to other infections.
"Pediatricians know firsthand that children's immune systems perform better after vaccination against serious, contagious diseases like polio, measles, whooping cough and Hepatitis B," the AAP stated. "Spacing out or delaying vaccines means children will not have immunity against these diseases at times when they are most at risk."
On leucovorin
The Trump administration also announced Monday that it was starting the approval process for a drug called leucovorin as a possible treatment for autism.
Leucovorin, which is typically used as part of cancer care, has shown early promise in a handful of small studies suggesting it may help the symptoms of some children with autism, but experts caution there is little evidence to support those statements.
The Coalition of Autism Scientistsreleased a statementcautioning that it's too soon to recommend leucovorin as a treatment.
The group said there are a few small trials examining the drug's use that are methodologically weak, use questionable statistical approaches, and do not justify clinical recommendations.
"The Coalition of Autism Scientists reviewed these studies and found that the researchers aren't using high-quality study designs or statistical analysis," the group stated.
The coalition called for a rigorous, large-scale trial with validated biomarkers and pre-registered endpoints. The group also reaffirmed that vaccines are safe, play no role in autism and that undermining them endangers public health. The group called for the Department of Health and Human Services to invest in high-quality, peer-reviewed autism research with independent oversight.
Additionally, the Autism Society of America (ASA) condemned the White House for promoting what it says are "unfounded" claims about causes and treatments.
The group stressed that autism is a lifelong, complex condition with no single cause or cure, and that premature claims about acetaminophen or leucovorin ignore decades of rigorous research and risk creating false hope and harm.
ASA said research on high-dose leucovorin is still in preliminary stages and that its safety must be understood before it is recommended for use among those with autism.
"Announcing a cause or treatment without rigorous, replicated science undermines trust and distracts from critical work needed for the autism community," the ASA's Board of Directors said in astatement. "What autistic individuals and their caregivers need are expanded services, inclusive policies, and research that helps improve quality of life."
